Description
Human induced pluripotent stem cells (hiPSCs) are reprogrammed adult cells capable of self-renewal and differentiation into virtually any cell type, making them a powerful and versatile platform for modern biomedical research. hiPSCs enable the creation of patient-specific models that capture genetic diversity and disease-relevant phenotypes, supporting applications in drug discovery, toxicity testing, regenerative medicine, and personalized therapeutics. Their ability to generate complex derivatives—including neurons, glia, cardiomyocytes, and organoids—allows researchers to study human development and disease mechanisms with far greater accuracy than traditional cell lines or animal models. With their scalability, reproducibility, and human relevance, hiPSCs have become a foundational tool for advancing translational science and accelerating innovation across multiple therapeutic areas.
The MAPT iPSC collections are now available to investigators in both for-profit and non-profit organizations.
For more information about the collections, and the documentation process required to obtain these lines please visit our NSCI Tau Consortium page. This recent publication covers the analysis performed on the cell lines.
