Description

Retinal pigment epithelial (RPE) cells play a critical role in maintaining photoreceptor health and visual function, making them an essential model system for studying retinal biology and disease. iPSC-derived RPE cells provide a reliable, human-relevant platform that replicates key physiological properties such as pigment formation, polarized morphology, phagocytic activity, and growth factor secretion. These high-fidelity RPE models enable researchers to investigate mechanisms underlying retinal degeneration, evaluate therapeutic targets, and perform drug screening with greater translational relevance than traditional 2D or animal-based systems.