Disease Models
Human-Relevant. Mechanistically Insightful. Built for Discovery.
NeuraCell develops advanced human brain organoid models that recapitulate key features of neurological disease. Built using patient-derived and genetically engineered iPSCs, our disease models provide powerful platforms for studying disease mechanisms, identifying biomarkers, evaluating therapeutic candidates, and accelerating translational neuroscience research.
By combining human-relevant biology with standardized manufacturing and rigorous quality control, NeuraCell enables researchers to generate more predictive data and gain deeper insights into complex neurological disorders.
Modeling Neurological Disease with Human Brain Organoids
Human brain organoids provide unprecedented opportunities to study neurological disease in a three-dimensional, human-relevant environment. By recapitulating key aspects of brain development, cellular diversity, and neural network formation, organoids enable researchers to investigate disease mechanisms that cannot be fully modeled using traditional cell culture systems.
NeuraCell disease models support studies ranging from fundamental disease biology to therapeutic development, offering scalable platforms for translational neuroscience research.
Integrated Approaches. Deeper Insights.
Diseases We Model
Alzheimer’s Disease
Study amyloid pathology, tau dysfunction, neuroinflammation, synaptic impairment, and neuronal degeneration using human-relevant brain organoid systems.
Parkinson’s Disease
Investigate dopaminergic neuron vulnerability, alpha-synuclein pathology, mitochondrial dysfunction, and neurodegeneration.
Frontotemporal Dementia (FTD)
Model genetic and sporadic forms of FTD, including tau- and TDP-43-associated mechanisms.
Progressive Supranuclear Palsy (PSP)
Explore tau pathology, neuronal dysfunction, and disease progression in patient-derived systems.
Tauopathies and Related Disorders
Access disease-relevant models supporting mechanistic studies and therapeutic development across a broad spectrum of neurodegenerative diseases.
Our Disease Model Workflow
Tau Consortium Collection
Exclusive Access to Disease-Relevant iPSC Resources
NeuraCell provides access to the Tau Consortium Collection, a unique portfolio of genetically characterized patient-derived and isogenic control hiPSC lines representing Alzheimer’s disease, Frontotemporal Dementia (FTD), Progressive Supranuclear Palsy (PSP), and related tauopathies.
These resources support the development of advanced disease models for studying disease mechanisms, biomarker discovery, and therapeutic evaluation.