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# NeuraCell

Advanced Human Brain Organoid Technology

## Sitemaps

- [XML Sitemap](https://www.neuracell.org/sitemap.xml): Contains all public & indexable URLs for this website.

## Pages

- [Advancing Neuroscience Through Human Brain Organoid Innovation](https://www.neuracell.org/) - Advance neuroscience with human brain organoids: predictive models for discovery, therapy development, and translational science.
- [FAQ](https://www.neuracell.org/faq) - Learn how partners use NeuraCell’s human brain organoid platform for drug discovery, disease modeling, QC, and translational research.
- [About](https://www.neuracell.org/about) - Meet the NeuraCell team—experts in stem cell biology and neuroscience—backed by peer-reviewed publications advancing human brain organoid research.
- [Disease Models for Neuroscience](https://www.neuracell.org/disease-models-for-neuroscience) - Disease Models Human-Relevant. Mechanistically Insightful. Built for Discovery. NeuraCell develops advanced human brain organoid models that recapitulate key features of neurological disease. Built using patient-derived and genetically engineered iPSCs, our disease models provide powerful platforms for studying disease mechanisms, identifying biomarkers, evaluating therapeutic candidates, and accelerating translational neuroscience research. By combining human-relevant biology with standardized
- [Forebrain Cortical Organoid Quality](https://www.neuracell.org/cortical-organoid-quality) - Forebrain Cortical Organoid Quality High-quality forebrain cortical organoids demonstrate consistent morphology, defined cortical layer organization, and reproducible differentiation into key neuronal and glial subtypes. Reliable organoid formation begins with validated iPSC lines and is sustained through controlled aggregation, lineage-specific patterning, and rigorous environmental monitoring. Quality assessment includes evaluations of viability, structural integrity, cortical marker expression,
- [Contact Us](https://www.neuracell.org/contact) - Contact Us Our Location NeuraCell150 New Scotland Ave. Albany, NY 12208 Steven Lotz – DirectorPhone: (518) 694-8188 Fax: (518) 694-8187info@neuracell.org
- [Striatal Organoid Quality](https://www.neuracell.org/striatal-organoid-quality) - Striatal Organoid Quality For striatal cortical organoid production, each iPSC line undergoes rigorous pluripotency evaluation to ensure it meets NeuraCell’s minimum quality thresholds—typically exceeding 90% SSEA4 positivity, 85% TRA-1-60 positivity, and an average of 75% double-positive expression. These criteria are essential for generating robust, lineage-competent cells capable of forming high-fidelity striatal tissue models. Striatal organoids
- [Neural Spheroid Quality](https://www.neuracell.org/neural-spheroid-quality) - Neural Spheroid Quality High-quality neural spheroids are defined by their uniform size, structural integrity, and reproducible differentiation into early neural lineages. Consistent spheroid formation ensures balanced nutrient and oxygen diffusion, supporting healthy proliferation and reducing core necrosis. Rigorous quality control measures—such as assessments of viability, neural marker expression, morphology, and functional activity—help confirm that each
- [Midbrain Organoid Quality](https://www.neuracell.org/midbrain-organoid-quality) - Midbrain Organoid Quality Midbrain organoids are derived from 3D spheroids of human iPSCs. These cultures are exposed to key pattern factors (e.g. dual-SMAD inhibition, sonic hedgehog) to direct cells into midbrain cell fates. The timing of cell type maturation follows the expected time course of human cortical development. At 20 days, organoids are composed of

## Products

- [Forebrain Cortical Organoids](https://www.neuracell.org/product/forebrain-cortical-organoids) - Human iPSC-derived cortical organoids for modeling cortical development, neurodegenerative disease, and drug discovery with reproducible quality.
- [Human Induced Pluripotent Stem Cells (hiPSC)](https://www.neuracell.org/product/human-induced-pluripotent-stem-cells-hipsc) - Human iPSCs provide a scalable, patient-specific cell source for disease modeling, drug discovery, and organoid production.
- [Neural Progenitor Cells (NPC)](https://www.neuracell.org/product/neural-progenitor-cells-npc) - Human iPSC-derived neural progenitor cells offer a reliable, scalable model for early neurodevelopment, enabling consistent differentiation into neurons and glia for disease research and drug testing.
- [Neural Spheroids](https://www.neuracell.org/product/neural-spheroids) - Neural spheroids enable analysis of cell interactions, viability, and drug toxicity in 3D, bridging 2D assays and complex organoid models.
- [Striatal Organoids](https://www.neuracell.org/product/striatal-organoids) - Human striatal organoids enable evaluation of medium spiny neuron vulnerability, neurotoxicity, and target engagement in basal ganglia disorders.
- [Midbrain Organoids](https://www.neuracell.org/product/midbrain-organoids) - Human midbrain organoids enable assessment of dopaminergic neuron vulnerability, neurotoxicity, and mechanisms that bridge preclinical and clinical research.
- [Retinal Pigment Epithelium (RPE) Cells](https://www.neuracell.org/product/primary-and-ipsc-derived-retinal-pigment-epithelium-rpe-cells) - Human adult polarized RPE cells for AMD, inherited retinal disease, and regenerative medicine research with consistent morphology and function.
- [Robust Contract Research Services](https://www.neuracell.org/product/contract-research-services) - NeuraCell delivers 3D models for drug screening, cell marker analysis, custom DNA and shRNA constructs, growth marker analysis, and high-quality stem cell contract research services.

## Product categories

- [Neural Organoids](https://www.neuracell.org/product-category/cell-supply/neural-organoids) - NeuraCell’s neural organoids provide researchers with high-fidelity, human-relevant 3D brain models derived from induced pluripotent stem cells (iPSCs). Designed to recapitulate region-specific tissue architecture and multicellular interactions, these organoids offer powerful platforms for neuroscience, drug discovery, and disease modeling. We routinely produce cortical, midbrain, and custom-patterned organoids from well-characterized wild-type iPSC donors. In addition, NeuraCell offers exclusive access to more than 100 genetically defined lines—including MAPT-mutant and matched isogenic controls from the Tau Consortium iPSC Collection—enabling rigorous genotype–phenotype studies and translational neurodegeneration research. Researchers may also submit their own iPSC lines for bespoke organoid generation. Organoids can be ordered at defined maturation stages (2, 4, and 6 months) and are available as live cultures or snap-frozen samples. To support robust, reproducible science, we encourage incorporating organoids from multiple donor backgrounds. Contact us for current inventory, custom options, and pricing details.
- [Cell Supply](https://www.neuracell.org/product-category/cell-supply) - NeuraCell has an extensive collection of cell lines and neural products for distribution, including iPSCs, Neural Progenitor Cells (NPCs), Schwann Cell Progenitors, Retinal Pigment Epithelial (RPE) cells and Neural Organoids.
- [Services](https://www.neuracell.org/product-category/services) - Our experienced staff provides a suite of services including reprogramming, differentiation, organoid culture and more.
- [Neural Cells](https://www.neuracell.org/product-category/cell-supply/neural-cells)

## Product tags

- [midbrain organoid](https://www.neuracell.org/product-tag/midbrain-organoid)
- [RPE cells](https://www.neuracell.org/product-tag/rpe-cells)
- [striatal organoid](https://www.neuracell.org/product-tag/striatal-organoid)
- [neural spheroids](https://www.neuracell.org/product-tag/neural-spheroids)
- [IPSC](https://www.neuracell.org/product-tag/ipsc)
- [forebrain cortical organoid](https://www.neuracell.org/product-tag/forebrain-cortical-organoid)